Este fenómeno es conocido como efecto Jod-Basedow. El tratamiento con propiltiouracilo en dosis decrecientes consiguió un estado eutiroideo y mejoró la . Efectos de las hormomas tiroideas en el corazón. Visits . por el efecto de Wolff- Chaikoff, además de hipertiroidismo (mediado por el efecto de Jod-Basedow. de hipertiroidismo (mediado por el efecto de Jod-Basedow. En ambos casos, la causa subyacente es por la alta concentración de yodo en este medicamento.

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Eur Radiol ;14 5: Subclinical thyroid dysfunction and mortality: The Jod-Basedow effect has also been seen as a side effect of administration of the iodine-containing contrast agents, or amiodaronean antiarrhythmic drug.

Nephrol Dial Transplant ;22 4: Mico Magister en Epidemiolog Clica.

The Jod-Basedow phenomenon is differentiated from Basedow’s diseasewhich is occasionally used as a synonym for Graves disease. Subclinical thyroid dysfunction is relatively common in patients over 65 years of age. Hyperthyreoserisiko bei Kontrastmittelun- tersuchungen.

However, unlike the Wolff-Chaikoff effectthe Jod-Basedow effect does not occur in persons with normal thyroid glands, as thyroid hormone synthesis and release in normal persons is controlled by pituitary TSH secretion which does not allow hyperthyroidism when extra iodine is ingested. Consequently, thyroid hormone deficiencies, as well as excesses, are expected to result in profound changes in cardiac function regulation and cardiovascular hemodynamics.


The effect is rapid because of rapid inhibition of intrathyroid organification of iodide acute Wolff—Chaikoff effect and saturation of the iodide-transport mechanism. Por el contrario, cuando un tirocito contiene valores bajos de yodo y es expuesto a elevadas concentraciones del mismo, aumenta de forma significativa la producci de hormona tiroidea, llevando frecuentemente a efexto clico y bioquico, feneno conocido como efecto de Jod-Basedow.

This phenomenon is thus iodine-induced hyperthyroidismtypically presenting in a patient with endemic goiter due to iodine deficiencywho relocate to an iodine-abundant geographical area. Patients with Graves’ disease are more sensitive than euthyroid patients, [5] and iodine basfdow been used to manage Graves’ disease. Previous article Next article. Jan Wolff and Israel Lyon Chaikoff at the University of California, is a presumed reduction in thyroid hormone levels caused by ingestion of a large amount of iodine.

The Jod-Basedow effect is named for the German word for iodine”Jod” all nouns are capitalized in Germanplus the name of Karl Adolph von Basedowa German physician who first described the effect. M, Bhan I, Alexander E. Print Send to a friend Export bsaedow Mendeley Statistics. CiteScore measures average citations received per document published.

Effects of thyroid hormones on the heart | Clínica e Investigación en Arteriosclerosis

The Wolff—Chaikoff effect is known as an autoregulatory phenomenon that inhibits organification in the thyroid glandthe formation of thyroid hormones inside the thyroid follicle, and the release of thyroid hormones into the bloodstream. People who have Graves diseasetoxic multinodular goiteror various types of thyroid adenoma are also at risk of Jod-Basedow effect when they ingest extra iodine.


Iodine and thyroid disease. Hospital Departamental Santa Sof de Caldas. Goodman and Gilman’s the pharmacological basis of therapeutics 9th ed.

Jod Basedow

Kid- ney Int Suppl ; Blood sugar regulation Calcium metabolism. Both hypothyroidism and hyperthyroidism increase the risk of coronary artery disease, left cardiomyopathy, electrophysiological abnormalities, and all-cause mortality. To improve our services and products, we use “cookies” own or third parties authorized to show advertising related to client preferences through the analyses of navigation customer behavior.

Subscribe to our Newsletter. Retrieved efecro ” https: Universidad Tecnolica de Pereira, Risaralda. SJR uses a similar algorithm as the Google page rank; it provides a quantitative and qualitative measure of the journal’s impact. The Wolff—Chaikoff effect[1] discovered by Drs.

Wolff–Chaikoff effect – Wikipedia

It is named after the German physician Karl Adolph von Basedow. Hypothalamic—pituitary—thyroid axis Hypothalamic—pituitary—adrenal axis Hypothalamic—pituitary—gonadal axis Hypothalamic—pituitary—somatotropic axis Hypothalamic—pituitary—prolactin axis Hypothalamic—neurohypophyseal system Renin—angiotensin system.

Am J Med ;95 1: Acta radiol ;54 1: Med J Aust ; 4: